Composition

Each tablet contains:

• Anastrozole – 1 mg
• Excipients – q.s.

Pharmacological Effects

• Aromatase Inhibitor (AI): Non-Steroidal, Reversible (Type II).
• Primary Action: Competitively binds to the aromatase enzyme, blocking the conversion of androgens (testosterone, androstenedione) into estrogen (estradiol).
• Result: Reduces circulating estrogen levels by 50–70% (dose-dependent).

Indications

• Adjuvant treatment of Estrogen-Receptor-Positive (ER+) breast cancer in postmenopausal women.
• Prevention of breast cancer recurrence.
• Estrogen control in testosterone/anabolic steroid cycles (prevents gynecomastia, water retention).
• Post-Cycle Therapy (PCT) – sometimes used alongside SERMs (e.g., Clomid, Nolvadex).

Recommended Dose

• Breast Cancer: 1 mg once daily (oral, with or without food).
• TRT/Steroid Cycle Use: 0.25–0.5 mg every other day (adjust based on bloodwork).
• Low-Dose TRT (100–200 mg/week testosterone): Often 0.25 mg twice weekly is sufficient.
• High-Dose Cycles (500+ mg/week testosterone): May require 0.5 mg every other day or 1 mg EOD (varies by individual).
• Note: Do NOT crush tablets (can alter absorption).

Side Effects

• Common: Low estrogen symptoms (joint pain, dry skin, reduced libido, mood swings), hot flashes, mild fatigue or headaches.
• Serious (rare but possible): Osteoporosis (long-term use without proper hormone balance), cardiovascular risks (due to low estrogen), elevated liver enzymes, depression/anxiety from crashed estrogen.

Contraindication

• Premenopausal women (can cause ovarian hyperstimulation).
• Pregnancy/lactation (estrogen suppression harms fetal development).
• Severe liver/kidney disease.
• Allergy to Exemestane or other AIs (e.g., Anastrozole, Letrozole).

Storage Conditions

• Store at room temperature (20–25°C / 68–77°F).
• Protect from moisture and light (keep in original packaging).
• Do not use if discolored or crumbled.

Disclaimer: Always follow your healthcare provider’s advice regarding storage and use, especially when dealing with compounds that have limited clinical data.